Showing posts with label family violence. Show all posts
Showing posts with label family violence. Show all posts

Sunday, June 22, 2014

Child abuse 'has serious consequences for brain development', Family violence leaves genetic imprint on children

Child abuse 'has serious consequences for brain development'
Sunday 22 June 2014 
A new study recently published in the American Journal of Psychiatry has found an association between child abuse and the reduction of gray matter in the brain that is responsible for information processing.

Child abuse, also referred to as child maltreatment, describes all forms of physical and emotional abuse, sexual abuse, neglect, negligence and any other exploitation that harms the health, development, dignity or survival of a child under the age of 18 years.

The World Health Organization (WHO) state that worldwide, around 20% of women and 5-10% of men report being sexually abused as children, while 23% of individuals report being physically abused during childhood....

The studies included 56 children or adolescents and 275 adults with a history of childhood abuse, as well as 56 children and 306 adults who had not been exposed to childhood maltreatment.

Using a 3D meta-analytical neuroimaging technique created by Radua - called "signed differential mapping" - the team was able to determine the volumes of gray matter in each individual.

They found that the individuals who had been exposed to childhood maltreatment had much smaller volumes of gray matter in certain brain areas, compared with those who had no history of child abuse....
http://www.medicalnewstoday.com/articles/278537.php 


Family violence leaves genetic imprint on children
June 17, 2014 Tulane University
Summary:
Children in homes affected by violence, suicide, or the incarceration of a family member have significantly shorter telomeres -— a cellular marker of aging -- than those in stable households. The study suggests that the home environment is an important intervention target to reduce the biological impacts of adversity in the lives of young children.

Researchers discovered that children in homes affected by domestic violence, suicide or the incarceration of a family member have significantly shorter telomeres, which is a cellular marker of aging, than those in stable households. The findings are published online in the latest issue of the journal Pediatrics.

Telomeres are the caps at the end of chromosomes that keep them from shrinking when cells replicate. Shorter telomeres are linked to higher risks for heart disease, obesity, cognitive decline, diabetes, mental illness and poor health outcomes in adulthood. Researchers took genetic samples from 80 children ages 5 to 15 in New Orleans and interviewed parents about their home environments and exposures to adverse life events.

"Family-level stressors, such as witnessing a family member get hurt, created an environment that affected the DNA within the cells of the children," said lead author Dr. Stacy Drury, director of the Behavioral and Neurodevelopmental Genetics Laboratory at Tulane. "The greater the number of exposures these kids had in life, the shorter their telomeres were -- and this was after controlling for many other factors, including socioeconomic status, maternal education, parental age and the child's age."

S. S. Drury, E. Mabile, Z. H. Brett, K. Esteves, E. Jones, E. A. Shirtcliff, K. P. Theall. The Association of Telomere Length With Family Violence and Disruption. PEDIATRICS, 2014; 134 (1): e128 DOI: 10.1542/peds.2013-3415
http://www.sciencedaily.com/releases/2014/06/140617102505.htm 

The Association of Telomere Length With Family Violence and Disruption

    Stacy S. Drury, MD, PhDa,
    Emily Mabile, BAb,
    Zoë H. Brett, PhDa,
    Kyle Esteves, BAa,
    Edward Jones, BAa,
    Elizabeth A. Shirtcliff, PhDc, and
    Katherine P. Theall, PhDb

....RESULTS: Cumulative exposure to interpersonal violence and family disruption was correlated with bTL. Controlling for other sociodemographic factors, bTL was significantly shorter in children with higher exposure to family violence and disruption. Witnessing family violence exerted a particularly potent impact. A significant gender interaction was found (ß = -0.0086, SE = 0.0031, z test= -2.79, P = .0053) and analysis revealed the effect only in girls.

CONCLUSIONS: bTL is a molecular biomarker of adversity and allostatic load that is detectable in childhood. The present results extend previous studies by demonstrating that telomeres are sensitive to adversity within the overarching family domain. These findings suggest that the family ecology may be an important target for interventions to reduce the biological impact of adversity in the lives of children.
http://pediatrics.aappublications.org/content/early/2014/06/10/peds.2013-3415 

Wednesday, November 21, 2012

Embattled Childhoods May Be the Real Trauma for Soldiers With PTSD

Embattled Childhoods May Be the Real Trauma for Soldiers With PTSD 

ScienceDaily (Nov. 19, 2012) — New research on posttraumatic stress disorder (PTSD) in soldiers challenges popular assumptions about the origins and trajectory of PTSD, providing evidence that traumatic experiences in childhood -- not combat -- may predict which soldiers develop the disorder....

"Most studies on PTSD in soldiers following service in war zones do not include measures of PTSD symptoms prior to deployment and thus suffer from a baseline problem. Only a few studies have examined pre- to post-deployment changes in PTSD symptoms, and most only use a single before-and-after measure," says Berntsen....

Rather than following some sort of "typical" pattern in which symptoms emerge soon after a particularly traumatic event and persist over time, Berntsen and colleagues found wide variation in the development of PTSD among the soldiers.

The vast majority of the soldiers (84%) were resilient, showing no PTSD symptoms at all or recovering quickly from mild symptoms.

The rest of the soldiers showed distinct and unexpected patterns of symptoms. About 4% showed evidence of "new-onset" trajectory, with symptoms starting low and showing a marked increase across the five timepoints. Their symptoms did not appear to follow any specific traumatic event.

Most notably, about 13% of the soldiers in the study actually showed temporary improvement in symptoms during deployment. These soldiers reported significant symptoms of stress prior to leaving for Afghanistan that seemed to ease in the first months of deployment only to increase again upon their return home.

What could account for this unexpected pattern of symptoms?

Compared to the resilient soldiers, the soldiers who developed PTSD were much more likely to have suffered emotional problems and traumatic events prior to deployment. Childhood experiences of violence, especially punishment severe enough to cause bruises, cuts, burns, and broken bones actually predicted the onset of PTSD in these soldiers. Those who showed symptoms of PTSD were more likely to have witnessed family violence, and to have experienced physical attacks, stalking or death threats by a spouse. They were also more likely to have past experiences that they could not, or would not, talk about. And they were less educated than the resilient soldiers....

The findings challenge the notion that exposure to combat and other war atrocities is the main cause of PTSD.

"We were surprised that stressful experiences during childhood seemed to play such a central role in discriminating the resilient versus non-resilient groups," says Berntsen. "These results should make psychologists question prevailing assumptions about PTSD and its development."

http://www.sciencedaily.com/releases/2012/11/121119140625.htm 


Peace and War Trajectories of Posttraumatic Stress Disorder Symptoms Before, During, and After Military Deployment in Afghanistan

Dorthe Berntsen, Kim B. Johannessen, Yvonne D. Thomsen, Mette Bertelsen, Rick H. Hoyle and David C. Rubin

Abstract
In the study reported here, we examined posttraumatic stress disorder (PTSD) symptoms in 746 Danish soldiers measured on five occasions before, during, and after deployment to Afghanistan. Using latent class growth analysis, we identified six trajectories of change in PTSD symptoms. Two resilient trajectories had low levels across all five times, and a new-onset trajectory started low and showed a marked increase of PTSD symptoms. Three temporary-benefit trajectories, not previously described in the literature, showed decreases in PTSD symptoms during (or immediately after) deployment, followed by increases after return from deployment. Predeployment emotional problems and predeployment traumas, especially childhood adversities, were predictors for inclusion in the nonresilient trajectories, whereas deployment-related stress was not.

These findings challenge standard views of PTSD in two ways. First, they show that factors other than immediately preceding stressors are critical for PTSD development, with childhood adversities being central. Second, they demonstrate that the development of PTSD symptoms shows heterogeneity, which indicates the need for multiple measurements to understand PTSD and identify people in need of treatment.

http://pss.sagepub.com/content/early/2012/11/02/0956797612457389